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Showing posts with label Melatonin. Show all posts
Showing posts with label Melatonin. Show all posts

Monday, December 12, 2011

Day 287- East Coast Jet Lag

I made it back from another East Coast business trip. Traveling to a different time zone can be exhausting; especially when the seminar starts at 8 am EST, and you have to be there at least an hour early, and you have to get up early enough to look presentable. So basically I am up by around 2:30 am PST and have to make sure I'm chipper and functioning. Good thing I'm still young right? I'm pretty resilient, and can bound back pretty quick.

But what happens when I'm still traveling and I'm not that spring chicken anymore? As it is all ready I always have a restless first night when I arrive to the East Coast. So I looked into some tips when it comes to avoiding jet lag while traveling. Here are some traveling tips that I found that I liked that didn't involve sleeping pills!

  • The first night arriving to a new location make sure to stay up until your normal bed time. So for me I am usually in bed by 10 pm PST, so when traveling to the east coast even though it may only be 7 pm PST and 10 pm EST make that your bed time. Then in the morning wake up at your normal wake-up time. So that would be 6 am EST, but 3 am PST. Don't go to bed before your normal bed time. I also found a recommendation that says to make sure you stay up until 11 pm no matter what time zone you are in, and not to sleep any sooner.
  • Don't take a nap once you arrive to your location. A short nap on the plane is fine, but don't take a nap after that. It will make it much more difficult to sleep at night.
  • Melatonin- Although I never would recommend melatonin, every once in awhile while traveling to help with sleep during time zone differences might be what it takes for some people. I wouldn't recommend taking it more than 2 days during travel. Melatonin is a natural hormone that helps to initiate the sleep process.
  • Homeopathic Remedies- I am a true believer of the benefits of homeopathics, there are some great ones out there that help to regulate the circadian rhythm.
  • Drink plenty of water; it is vital to stay hydrated. Avoid alcohol (especially on the plane) and caffeine, which can both lead to dehydration and interrupt sleep.
Safe Travels!

Pura Vida!
Alica Ryan, NTP

Saturday, June 11, 2011

Day 103- Dream Water

So, needless to say I have been spending a lot of time at airports lately, probably more so than at my own home. This weekend when I was at one of the news stands I noticed a new product, called Dream Water. Packaged in a similar bottle to that of 5 hour energy, but in a white bottle with light blue font in order to make it look more peaceful and relaxing, and small enough so that you can get them through airport security. They offer flavors such as snoozeberry, I dream of kiwi, and lullaby lemon. And advertise as a natural way to sleep better, without the use of harmful chemicals found in medications; targeting those of us that are experiencing jet lag.

Dream Water, sounds harmless enough right?

Well...it may not be as harmless as they want us to think. Here's the deal, 2 out of the 3 key natural ingredients that the product is based on are not recommended to use for supplementation. The product includes GABA to help you relax, Melatonin to help induce sleep, and 5 HTP to promote sleep and relaxation.

First of all the ingredient, Gamma-amino butyric acid (GABA), is the chief inhibitory neurotransmitter; although it may have enhancing properties as well. Gabergenic responses are linked with relaxation, anti-anxiety, and anti-convulsive effects. Sounds like the perfect ingredient for Dream Water, right? Well, there is a major problem with taking GABA as a oral supplement; it can not cross the blood brain barrier to have a gabergenic effect, since it is such a large neurotransmitter. But then why if that is the case do people take GABA supplements to relax themselves? If you take GABA and notice more relaxation, or less anxiety, chances are you have a leaky blood brain barrier, that is allowing GABA to cross through.

If you are having a hard time relaxing, feel anxious for no reason, feel overwhelmed, then you many need to support the GABA neurotransmitter, NOT by taking actual oral GABA supplementation, but by supporting GABA cofactors, providing GABA amino acid precursors, and providing GABA receptor modulators (Vaalerian root, Lithium Orotate, Passion flower extract, L-Theanine, Taurine).

Melatonin is a hormone that is naturally produced by the pineal gland in the brain. It has an inverse effect with Cortisol, and plays a major role in sleep and wake cycles. In normal rhythm melatonin levels tend to rise gradually in the evening, remain high during the night, and then drop in the early morning hours. In research studies Melatonin was shown to be safe for short-term use (3 months), but is not recommended for much longer.

Sounds like another great supplement to help catch up on sleep right? The problem that we find with use of melatonin supplementation is that it can actually cause long term effects on the circadian rhythm. Since melatonin and cortisol are inversely related, the intake of melatonin can throw off the delicate cycle of cortisol, leading to a dependancy on melatonin in the future. So instead of directly addressing the circadian rhythm, my advice is to go after the factors that could be throwing your circadian rhythm off balance; diet, caffeine, sleep cycles, stress, anemia, medications, etc.

5-hydroxytryptophan (5-HTP) is actually an amino acid precursor to serotonin. It is the intermediate step between tryptophan and serotonin (5-HT). It has been shown to increase serotonin levels and decrease insomnia due to depression. It has also been shown as an effective compound for persistent nightmares, fibromylagia, chronic daily headaches, migraines, and mood disorders. 5-HTP is able to cross the blood brain barrier unlike 5-HT and with the help of B6 is decarboxylated to serotonin.

Although this supplement has been shown to have great effects, beware of taking this if you are on anti-depressants, because 5-HTP can increase the activity of these drugs. It is also warned against taking if you are pregnant, nursing, or have significant cardiovascular disease.

So, having trouble sleeping, jet-lagged, or anxious? Instead of spending your money on dreams in a bottle, get to the root of the issue. One of the biggest causes of sleep disorders is blood sugar dysregulation and adrenal stress. So start there and see if you still need to count sheep to fall asleep.


Pura Vida!
Alica Ryan, NTP



  • Sevenja L Mayer R. et al. Interaction of valerian extracts of different polarity with adenosine receptors: Identification of isovaltrate as an inverse agonist at A1 receptors. Biochemical Pharmacology 2007; 73:248-258
  • Santos MS, Ferreira F, et al. Synatposmal GABA releases as influenced by valerian root extract- involvement of the GABA carrier. Arch Int Pharmacodyn Ther 1994; 327:220-31
  • Schrauzer GN. Effects of nutritional lithium supplementation on mood. Biol Trace El Res 1994; 40:89-101
  • Dhawan K, Kumar S, Sharma A. Anti-anxiety studies on extracts of Passiflora incarnata Linneaus. Journal of Ethnopharmacology. 2001; 25(5):369-373
Showing posts with label Melatonin. Show all posts
Showing posts with label Melatonin. Show all posts

Monday, December 12, 2011

Day 287- East Coast Jet Lag

I made it back from another East Coast business trip. Traveling to a different time zone can be exhausting; especially when the seminar starts at 8 am EST, and you have to be there at least an hour early, and you have to get up early enough to look presentable. So basically I am up by around 2:30 am PST and have to make sure I'm chipper and functioning. Good thing I'm still young right? I'm pretty resilient, and can bound back pretty quick.

But what happens when I'm still traveling and I'm not that spring chicken anymore? As it is all ready I always have a restless first night when I arrive to the East Coast. So I looked into some tips when it comes to avoiding jet lag while traveling. Here are some traveling tips that I found that I liked that didn't involve sleeping pills!

  • The first night arriving to a new location make sure to stay up until your normal bed time. So for me I am usually in bed by 10 pm PST, so when traveling to the east coast even though it may only be 7 pm PST and 10 pm EST make that your bed time. Then in the morning wake up at your normal wake-up time. So that would be 6 am EST, but 3 am PST. Don't go to bed before your normal bed time. I also found a recommendation that says to make sure you stay up until 11 pm no matter what time zone you are in, and not to sleep any sooner.
  • Don't take a nap once you arrive to your location. A short nap on the plane is fine, but don't take a nap after that. It will make it much more difficult to sleep at night.
  • Melatonin- Although I never would recommend melatonin, every once in awhile while traveling to help with sleep during time zone differences might be what it takes for some people. I wouldn't recommend taking it more than 2 days during travel. Melatonin is a natural hormone that helps to initiate the sleep process.
  • Homeopathic Remedies- I am a true believer of the benefits of homeopathics, there are some great ones out there that help to regulate the circadian rhythm.
  • Drink plenty of water; it is vital to stay hydrated. Avoid alcohol (especially on the plane) and caffeine, which can both lead to dehydration and interrupt sleep.
Safe Travels!

Pura Vida!
Alica Ryan, NTP

Saturday, June 11, 2011

Day 103- Dream Water

So, needless to say I have been spending a lot of time at airports lately, probably more so than at my own home. This weekend when I was at one of the news stands I noticed a new product, called Dream Water. Packaged in a similar bottle to that of 5 hour energy, but in a white bottle with light blue font in order to make it look more peaceful and relaxing, and small enough so that you can get them through airport security. They offer flavors such as snoozeberry, I dream of kiwi, and lullaby lemon. And advertise as a natural way to sleep better, without the use of harmful chemicals found in medications; targeting those of us that are experiencing jet lag.

Dream Water, sounds harmless enough right?

Well...it may not be as harmless as they want us to think. Here's the deal, 2 out of the 3 key natural ingredients that the product is based on are not recommended to use for supplementation. The product includes GABA to help you relax, Melatonin to help induce sleep, and 5 HTP to promote sleep and relaxation.

First of all the ingredient, Gamma-amino butyric acid (GABA), is the chief inhibitory neurotransmitter; although it may have enhancing properties as well. Gabergenic responses are linked with relaxation, anti-anxiety, and anti-convulsive effects. Sounds like the perfect ingredient for Dream Water, right? Well, there is a major problem with taking GABA as a oral supplement; it can not cross the blood brain barrier to have a gabergenic effect, since it is such a large neurotransmitter. But then why if that is the case do people take GABA supplements to relax themselves? If you take GABA and notice more relaxation, or less anxiety, chances are you have a leaky blood brain barrier, that is allowing GABA to cross through.

If you are having a hard time relaxing, feel anxious for no reason, feel overwhelmed, then you many need to support the GABA neurotransmitter, NOT by taking actual oral GABA supplementation, but by supporting GABA cofactors, providing GABA amino acid precursors, and providing GABA receptor modulators (Vaalerian root, Lithium Orotate, Passion flower extract, L-Theanine, Taurine).

Melatonin is a hormone that is naturally produced by the pineal gland in the brain. It has an inverse effect with Cortisol, and plays a major role in sleep and wake cycles. In normal rhythm melatonin levels tend to rise gradually in the evening, remain high during the night, and then drop in the early morning hours. In research studies Melatonin was shown to be safe for short-term use (3 months), but is not recommended for much longer.

Sounds like another great supplement to help catch up on sleep right? The problem that we find with use of melatonin supplementation is that it can actually cause long term effects on the circadian rhythm. Since melatonin and cortisol are inversely related, the intake of melatonin can throw off the delicate cycle of cortisol, leading to a dependancy on melatonin in the future. So instead of directly addressing the circadian rhythm, my advice is to go after the factors that could be throwing your circadian rhythm off balance; diet, caffeine, sleep cycles, stress, anemia, medications, etc.

5-hydroxytryptophan (5-HTP) is actually an amino acid precursor to serotonin. It is the intermediate step between tryptophan and serotonin (5-HT). It has been shown to increase serotonin levels and decrease insomnia due to depression. It has also been shown as an effective compound for persistent nightmares, fibromylagia, chronic daily headaches, migraines, and mood disorders. 5-HTP is able to cross the blood brain barrier unlike 5-HT and with the help of B6 is decarboxylated to serotonin.

Although this supplement has been shown to have great effects, beware of taking this if you are on anti-depressants, because 5-HTP can increase the activity of these drugs. It is also warned against taking if you are pregnant, nursing, or have significant cardiovascular disease.

So, having trouble sleeping, jet-lagged, or anxious? Instead of spending your money on dreams in a bottle, get to the root of the issue. One of the biggest causes of sleep disorders is blood sugar dysregulation and adrenal stress. So start there and see if you still need to count sheep to fall asleep.


Pura Vida!
Alica Ryan, NTP



  • Sevenja L Mayer R. et al. Interaction of valerian extracts of different polarity with adenosine receptors: Identification of isovaltrate as an inverse agonist at A1 receptors. Biochemical Pharmacology 2007; 73:248-258
  • Santos MS, Ferreira F, et al. Synatposmal GABA releases as influenced by valerian root extract- involvement of the GABA carrier. Arch Int Pharmacodyn Ther 1994; 327:220-31
  • Schrauzer GN. Effects of nutritional lithium supplementation on mood. Biol Trace El Res 1994; 40:89-101
  • Dhawan K, Kumar S, Sharma A. Anti-anxiety studies on extracts of Passiflora incarnata Linneaus. Journal of Ethnopharmacology. 2001; 25(5):369-373